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The findings on chest imaging in DIPNECH patients are bilateral and diffuse. The most frequent findings on a computed tomography (CT) of the chest are multiple primary nodules and/or masses, on a background of mosaic attenuation and airway wall thickening. [2] [9] The nodules have an indolent pattern of growth and are found throughout the lungs.
Pneumatosis is the abnormal presence of air or other gas within tissues. [1] In the lungs, emphysema involves enlargement of the distal airspaces, [2] and is a major feature of chronic obstructive pulmonary disease (COPD). Other pneumatoses in the lungs are focal (localized) blebs and bullae, pulmonary cysts and cavities.
Ground-glass opacity is among the most common imaging findings in patients with confirmed COVID-19. [16] [17] One systematic review found that among patients with COVID-19 and abnormal lung findings on CT, greater than 80% had GGOs, with greater than 50% having mixed GGOs and consolidation. [16]
Alveolar capillary dysplasia (ACD) is a rare, congenital diffuse lung disease characterized by abnormal blood vessels in the lungs that cause highly elevated pulmonary blood pressure and an inability to effectively oxygenate and remove carbon dioxide from the blood.
Since laboratory testing, imaging, and bronchoalveolar lavage results are often non-specific, guidelines recommend surgical biopsy to diagnose desquamative interstitial pneumonia if high-resolution computed tomography does not reveal classic signs of interstitial pneumonia. [17] A definitive diagnosis of DIP relies on a lung biopsy. [18]
A lung cavity or pulmonary cavity is an abnormal, thick-walled, air-filled space within the lung. [1] Cavities in the lung can be caused by infections, cancer, autoimmune conditions, trauma, congenital defects, [2] or pulmonary embolism. [3] The most common cause of a single lung cavity is lung cancer. [4]
When associated with significant airflow limitation, emphysema is a major subtype of chronic obstructive pulmonary disease (COPD), a progressive lung disease characterized by long-term breathing problems and poor airflow. [10] [11] Without COPD, the finding of emphysema on a CT lung scan still confers a higher mortality risk in tobacco smokers ...
Lung nodules can also occur in immune disorders, such as rheumatoid arthritis or granulomatosis with polyangiitis, or organizing pneumonia. A solitary lung nodule can be found to be an arteriovenous malformation, a hematoma or an infarction zone. It may also be caused by bronchial atresia, sequestration, an inhaled foreign body or pleural plaque.