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As described above, medications used to treat narcolepsy primarily target EDS and/or cataplexy. Internationally, there are differences in the availability of medications as well as guidelines for treatment. The alerting agents are medications typically used to improve wakefulness and include modafinil, armodafinil, pitolisant and solriamfetol.
Sodium oxybate, sold under the brand name Xyrem among others, is a medication used to treat symptoms of narcolepsy: sudden muscle weakness and excessive daytime sleepiness. [3] [7] [8] It is used sometimes in France and Italy as an anesthetic given intravenously.
[1] [14] [15] Adderall is indicated in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is also used illicitly as an athletic performance enhancer, cognitive enhancer, appetite suppressant, and recreationally as a euphoriant. It is a central nervous system (CNS) stimulant of the phenethylamine class. [1]
Wellbutrin and Adderall are two common prescription medications used by healthcare providers to treat anxiety and depressive disorders and ADHD, respectively. ... be used to treat narcolepsy (a ...
Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant and eugeroic (wakefulness promoter) medication used primarily to treat narcolepsy, [3] [8] [15] a sleep disorder characterized by excessive daytime sleepiness and sudden sleep attacks. [16]
Pitolisant is the first eugeroic drug that acts by blocking the histamine H 3 autoreceptor, which increases the activity of histamine neurons in the brain. Pitolisant has been shown to be effective and well-tolerated for the treatment of narcolepsy with or without cataplexy. [19] [20] [21]
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