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Destruction of the cingulate gyrus has been used in the treatment of psychosis. Such lesions result in akinesia, mutism, apathy, and indifference to painful stimuli. [7] The anterior cingulate cortex is thought to supply a "global energizing factor" that stimulates decision making. [8] When the anterior cingulate cortex is damaged, it can ...
The cingulate cortex includes the entire cingulate gyrus, which lies immediately above the corpus callosum, and the continuation of this in the cingulate sulcus. The cingulate cortex is usually considered part of the limbic lobe .
In cingulate or subfalcine herniation, the most common type, the innermost part of the frontal lobe is scraped under part of the falx cerebri, the dura mater at the top of the head between the two hemispheres of the brain. [8] [13] Cingulate herniation can be caused when one hemisphere swells and pushes the cingulate gyrus by the falx cerebri. [7]
Bilateral cingulotomy targets the anterior cingulate cortex, which is a part of the limbic system. This system is responsible for the integration of feelings and emotion in the human cortex. It consists of the cingulate gyrus, parahippocampal gyrus, amygdala, and the hippocampal formation. [8]
Broca named the limbic lobe in 1878, identifying it with the cingulate and parahippocampal gyri, and associating it with the sense of smell - Treviranus having earlier noted that, between species, the size of the parahippocampal gyrus varies with the size of the olfactory nerve. [2]
Nociplastic pain is caused by an altered function of pain-related sensory pathways in the periphery and the central nervous system, resulting in hypersensitivity. [88] Nociplastic pain is commonly referred to as "Nociplastic pain syndrome" because it is coupled with other symptoms. [16]
The adjacent subcallosal cingulate gyrus has been implicated in major depression and research indicates that deep-brain stimulation of the region could act to alleviate depressive symptoms. [36] Although people with depression had smaller subgenual ACCs, [ 37 ] their ACCs were more active when adjusted for size.
A summary of clinical manifestations of each syndrome can be found below, in the section labelled "Clinical presentation". [ citation needed ] The main patterns of polymicrogyria are: perisylvian (61%), generalised (13%), frontal (5%), and parasagittal parieto-occipital (3%) and 11% is associated with gray matter heterotopia ( grey matter is ...