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A carbogen mixture of 95% oxygen and 5% carbon dioxide can be used as part of the early treatment of central retinal artery occlusion.On this same premise it has also been proposed to be used in the management of sudden sensorineural hearing loss which can increase the blood flow to the inner ear and also possibly relieve the internal auditory artery spasm.
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Blood oxygen saturation may be used for hypoxic hypoxia, but is generally meaningless in other forms of hypoxia. In hypoxic hypoxia 95–100% saturation is considered normal; 91–94% is considered mild and 86–90% moderate. Anything below 86% is considered severe. [8] Cerebral hypoxia refers to oxygen levels in brain tissue, not blood.
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In response to oxygen levels 95% lower than normoxic conditions, apoptosis of ILCM increases lamellar surface area by up to 60% after just 24 hours. [62] However, this comes at a significant osmoregulatory cost, reducing sodium and chloride levels in the cytoplasm by over 10%. [ 62 ]
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Mitigation may be by supplementary oxygen, pressurisation of the habitat or environmental protection suit, or a combination of both. In all cases the critical effect is the raising of oxygen partial pressure in the breathing gas. [1] Room air at altitude can be enriched with oxygen without introducing an unacceptable fire hazard.