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  2. Methotrexate - Wikipedia

    en.wikipedia.org/wiki/Methotrexate

    Methotrexate was originally developed and continues to be used for chemotherapy, either alone or in combination with other agents.It is effective for the treatment of several cancers, including solid tumours of breast, head and neck, lung, bladder, as well as acute lymphocytic leukemias, non-Hodgkin's lymphoma, osteosarcoma, and choriocarcinoma and other trophoblastic neoplasms.

  3. Pharmacokinetics - Wikipedia

    en.wikipedia.org/wiki/Pharmacokinetics

    Elimination half-‍life: The time required for the concentration of the drug to reach half of its original value. ⁡ 12 h Elimination rate constant: The rate at which a drug is removed from the body.

  4. Modified-release dosage - Wikipedia

    en.wikipedia.org/wiki/Modified-release_dosage

    If the absorption of the active compound involves an active transport, the development of a time-release product may be problematic. The biological half-life of the drug refers to the drug's elimination from the bloodstream which can be caused by metabolism, urine, and other forms of excretion. If the active compound has a long half-life (over ...

  5. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...

  6. Median lethal dose - Wikipedia

    en.wikipedia.org/wiki/Median_lethal_dose

    A comparable measurement is LCt 50, which relates to lethal dosage from exposure, where C is concentration and t is time. It is often expressed in terms of mg-min/m 3. ICt 50 is the dose that will cause incapacitation rather than death.

  7. The good news is that the farrier is in the area and can shoe your horse right away. However, in all the excitement your horse is having far too much fun to be caught.

  8. Tocilizumab - Wikipedia

    en.wikipedia.org/wiki/Tocilizumab

    Tocilizumab, sold under the brand name Actemra among others, is an immunosuppressive drug, used for the treatment of rheumatoid arthritis, systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, giant cell arteritis, cytokine release syndrome, COVID‑19, and systemic sclerosis-associated interstitial lung disease (SSc-ILD).

  9. Conference foes No. 17 BYU and No. 23 Colorado will square off on Saturday night in the Alamo Bowl in San Antonio. The Cougars (10-2) and Buffaloes (9-3) once had their sights set on a Big 12 ...

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