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The 2024 Nobel Prize in chemistry has been awarded to a trio of scientists who used artificial intelligence to “crack the code” of almost all known proteins, the “chemical tools of life.”
Kickers, Inc. is a twelve-issue comic book series published by Marvel Comics from 1986 to 1987 as part of the New Universe imprint. Created by Tom DeFalco and Ron Frenz, the series featured a group of former professional American football players for the fictional New York Smashers team who became a group of heroes for hire, calling themselves "Kickers Inc."
Small proteins are a diverse fold class of proteins (usually <100 amino acids long). [ 1 ][ 2 ][ 3 ] Their tertiary structure is usually maintained by disulphide bridges, [ 4 ] metal ligands, [ 5 ] and or cofactors such as heme. Some small proteins serve important regulatory functions by direct interaction with certain enzymes and are therefore ...
Levinthal's paradox is a thought experiment in the field of computational protein structure prediction; protein folding seeks a stable energy configuration. An algorithmic search through all possible conformations to identify the minimum energy configuration (the native state) would take an immense duration; however in reality protein folding happens very quickly, even in the case of the most ...
Ubiquitin-like proteins (UBLs) are a family of small proteins involved in post-translational modification of other proteins in a cell, usually with a regulatory function. The UBL protein family derives its name from the first member of the class to be discovered, ubiquitin (Ub), best known for its role in regulating protein degradation through covalent modification of other proteins.
Gregory L. Verdine (born June 10, 1959) is an American chemical biologist, biotech entrepreneur, venture capitalist and university professor. [3] He is a founder of the field of chemical biology, [citation needed] which deals with the application of chemical techniques to biological systems. His work has focused on mechanisms of DNA repair and ...
A cystine knot is a protein structural motif containing three disulfide bridges (formed from pairs of cysteine residues). The sections of polypeptide that occur between two of them form a loop through which a third disulfide bond passes, forming a rotaxane substructure. The cystine knot motif stabilizes protein structure and is conserved in ...
The Ultimate Universe is an imprint of comic books published by Marvel Comics beginning in 2023. Reimagining several classic Marvel characters in a new fictional continuity, Jonathan Hickman and Bryan Hitch's Ultimate Invasion limited series depicted The Maker (the Reed Richards of Earth-1610) shaping a new world order in his image, resulting in Earth-6160, a new one preceded by alternate history.