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Hydrogels have a high water content, [7] with some hydrogels containing up to 90% water. [5] Active drugs and other substances dispersed as colloids or dissolved in water can be easily taken up by hydrogels. [5] Hydrogels are biocompatible. [5] [7] They also swell to a greater volume than organogels when in contact with water and other natural ...
A hydrogel is a biphasic material, a mixture of porous and permeable solids and at least 10% of water or other interstitial fluid. [1] [2] The solid phase is a water insoluble three dimensional network of polymers, having absorbed a large amount of water or biological fluids.
Polyvinyl alcohol (PVOH, PVA, or PVAl) is a water-soluble synthetic polymer.It has the idealized formula [CH 2 CH(OH)] n.It is used in papermaking, textile warp sizing, as a thickener and emulsion stabilizer in polyvinyl acetate (PVAc) adhesive formulations, in a variety of coatings, and 3D printing.
The primary role of many of these polymers was to act as a biocompatible cement in the fixation of prostheses and in the replacement of joints. Newer biologically compatible synthetic and natural biodegradable polymers have been developed; these include polyglycolide, polylactide, polyhydroxobutyrate, chitosan, hyaluronic acid, and hydrogels.
Bioadhesives are of commercial interest because they tend to be biocompatible, i.e. useful for biomedical applications involving skin or other body tissue. Some work in wet environments and under water, while others can stick to low surface energy – non-polar surfaces like plastic.
Self-healing hydrogels are a specialized type of polymer hydrogel.A hydrogel is a macromolecular polymer gel constructed of a network of crosslinked polymer chains. Hydrogels are synthesized from hydrophilic monomers by either chain or step growth, along with a functional crosslinker to promote network formation.
Hydrogel dressing is a medical dressing based on hydrogels, three-dimensional hydrophilic structure. [1] The insoluble hydrophilic structures absorb polar wound exudates and allow oxygen diffusion at the wound bed to accelerate healing. [ 2 ]
In the literature, one quite often stumbles upon the adjective form, ‘biocompatible’. However, according to Williams’ definition, this does not make any sense because biocompatibility is contextual, i.e. much more than just the material itself will determine the clinical outcome of the medical device of which the biomaterial is a part.
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