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Vaping-associated pulmonary injury (VAPI), [4] also known as vaping-associated lung injury (VALI) [1] or e-cigarette, or vaping, product use associated lung injury (E/VALI), [2] [a] is an umbrella term, [15] [16] used to describe lung diseases associated with the use of vaping products that can be severe and life-threatening. [3]
Vaping causes bronchospasm. [93] Adolescents who vaped had a higher frequency of chronic bronchitis symptoms. [133] A 2015 review reported that the long-term effects regarding respiratory flow resistance were unknown. [90] A 2014 review concluded that e-cigarettes reduced lung function, but much less than traditional cigarettes. [134]
CDC investigators identified direct exposure to chemicals present in illegal cannabis vaping products as the likely culprit, but did not rule out chemicals in nicotine vapes as possible causes. [9] CDC: "No specific e-cigarette device or substance has been linked to all cases, and e-cigarettes include a variety of chemical and additives".
Still, experts caution against vaping as a cure-all. Quitting nicotine use entirely is still the healthiest thing a person can do — even if they’ve been smoking or vaping for years. And some ...
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Smoking most commonly leads to diseases affecting the heart and lungs and will commonly affect areas such as hands or feet. First signs of smoking-related health issues often show up as numbness in the extremities, with smoking being a major risk factor for heart attacks, chronic obstructive pulmonary disease (COPD), emphysema, and cancer, particularly lung cancer, cancers of the larynx and ...
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The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...