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Diffuse alveolar damage (DAD) is a histologic term used to describe specific changes that occur to the structure of the lungs during injury or disease.Most often DAD is described in association with the early stages of acute respiratory distress syndrome (). [1]
It tends to arise in the distal bronchioles or alveoli and is defined by a non-invasive growth pattern. This small solitary tumor exhibits pure alveolar distribution (lepidic growth) and lacks any invasion of the surrounding normal lung. If completely removed by surgery, the prognosis is excellent with up to 100% 5-year survival. [1]
A physician will listen to the patient's lungs to help determine if there is likely a lower lung disease. Depending on the type of alveolar lung disease, the listener may hear "crackles" that indicate an excess of fluid in the lungs or an absence of lung sounds in certain regions which may indicate poor ventilation due to consolidation of pus ...
The prognosis for non-small cell lung cancer (NSCLC) can depend on several factors, including the stage of your disease. Survival rates also vary.
Chest radiography is usually the first test to detect interstitial lung diseases, but the chest radiograph can be normal in up to 10% of patients, especially early in the disease process. [17] [18] High-resolution CT of the chest is the preferred modality and differs from routine CT of the chest. Conventional (regular) CT chest examines 7–10 ...
Lung cancer is the most diagnosed and deadliest cancer worldwide, with 2.2 million cases in 2020 resulting in 1.8 million deaths. [3] Lung cancer is rare in those younger than 40; the average age at diagnosis is 70 years, and the average age at death 72. [2] Incidence and outcomes vary widely across the world, depending on patterns of tobacco use.
The tissue in the lungs becomes thick and stiff, which affects the tissue that surrounds the air sacs in the lungs. [7] Symptoms typically include gradual onset of shortness of breath and a dry cough. [1] Other changes may include feeling tired, and clubbing abnormally large and dome shaped finger and toenails. [1]
The onset of pulmonary hemorrhage is characterized by a cough productive of blood and worsening of oxygenation leading to cyanosis. [1] Treatment should be immediate and should include tracheal suction, oxygen, positive pressure ventilation , and correction of underlying abnormalities such as disorders of coagulation .