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Enalapril, sold under the brand name Vasotec among others, is an ACE inhibitor medication used to treat high blood pressure, diabetic kidney disease, and heart failure. [5] For heart failure, it is generally used with a diuretic , such as furosemide . [ 6 ]
Enalaprilat is the active metabolite of enalapril. It is the first dicarboxylate-containing ACE inhibitor and was developed partly to overcome these limitations of captopril. The thiol functional group of captopril was replaced with a carboxylic acid group, but additional modifications were required to achieve a potency similar to captopril.
Enalapril is a derivative, designed by scientists at Merck to overcome the rash and bad taste caused by captopril. [25] [26]: 12–13 Enalapril is actually a prodrug; the active metabolite is enalaprilat. [27]
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Enalapril/hydrochlorothiazide, sold under the brand name Vaseretic among others, is a fixed-dose combination medication used for the treatment of hypertension (high blood pressure). [2] It contains enalapril , an angiotensin converting enzyme inhibitor , and hydrochlorothiazide a diuretic . [ 2 ]
Apple stock jumped Monday, proving itself resilient to the widespread AI stock sell-off Monday prompted by the release of Chinese firm DeepSeek’s new cost-effective artificial intelligence model.
New tests done by the Environmental Working Group have found 21 oat-based cereals and snack bars popular amongst children to have "troubling levels of glyphosate." The chemical, which is the ...
173. enalapril meleate 174. enfenamic acid 175. epinephrine 176. epirubicine 177. eptifibatide 178. ergot, alkaloids of whether hydrogenated or not, their homologoues, salts 179. esomeprazole 180. estradiol succinate 181. estramustine phosphate 182. etanercept 183. ethacridine lactate 184. ethambutol hydrochloride 185. ethamsylate 186 ...