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Kratom use comes with many health risks, including cardiac arrest, kidney or liver damage, brain bleeding, and seizures. Some people have also died due to kratom overdose. View the original ...
Kratom overdose is a subject of concern in many countries because of the associated rising number of hospitalizations and deaths in which chronic kratom use is a contributing factor. [11] [16] According to clinical reviews, a kratom overdose can cause liver toxicity, seizures, coma, and death, [16] especially in combination with excessive ...
Liver damage, [3] nausea, vomiting, epigastric and abdominal pain, diarrhoea, anxiety, headache and convulsions, often followed by coma [10] Ayurvedic Herbo-mineral (Rasashastra) Medicines Heavy metal contamination [11] Bitter orange 'Fainting, arrhythmia, heart attack, stroke, death' [4] Broom
Mitragynine toxicity in humans is rarely reported although specific examples of seizures and liver toxicity in kratom consumers have been reported. [34] [32] Due to cytochrome P450 enzyme inhibition, the combination of mitragynine with other drugs poses concern for adverse reactions to mitragynine.
In smaller doses, kratom can produce stimulant effects, according to the Centers for Disease Control and Prevention. If taken in higher doses, it can produce effects similar to opioids.
Kratom has been used for hundreds of years in Southeast Asia for issues like fatigue. But it's banned in at least 6 states. Kratom is an herbal supplement with stimulant-like effects.
As for liver risks, Tejada says risks include liver toxicity, hepatitis, and liver failure, with toxicity believed to be dose-dependent and possibly due to excessive accumulation of catechins in ...
addictive drug – psychoactive substances that with repeated use are associated with significantly higher rates of substance use disorders, due in large part to the drug's effect on brain reward systems; dependence – an adaptive state associated with a withdrawal syndrome upon cessation of repeated exposure to a stimulus (e.g., drug intake)