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The drug has no estrogenic effects. [4] Mestanolone was discovered in 1935 and was introduced for medical use in the 1950s. [6] [7] [8] [4] In addition to its medical use, mestanolone has been used to improve physique and performance. [4] It was used in East Germany in Olympic athletes as part of a state-sponsored doping program in the 1970s ...
Mesterolone is the generic name of the drug and its INN Tooltip International Nonproprietary Name, USAN Tooltip United States Adopted Name, BAN Tooltip British Approved Name, and DCIT Tooltip Denominazione Comune Italiana, while mestérolone is its DCF Tooltip Dénomination Commune Française.
The drugs are controlled substances ... unlike DHT and the closely related DHT derivatives mestanolone ... Metenolone is the generic name of the drug and its INN ...
India exports generic drugs to the United States and the European Union. [23] also the according to market research community the Global Generic Drugs Market was evaluated US$465.96 million in 2021 and is expected to rise with a CAGR of 5.5% from 2022- 2028 during the forecast period. [24]
The drug is a synthetic androgen and anabolic steroid and hence is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT). [ 6 ] [ 8 ] It has moderate anabolic effects and weak androgenic effects, as well as no estrogenic effects or risk of liver damage .
The drug is metabolized in the liver by oxidation at the C2 position, reduction at the C3 position, hydroxylation at the C17 position, and conjugation. [ 6 ] [ 4 ] The C2 hydroxymethylene group of oxymetholone can be cleaved to form mestanolone (17α-methyl-DHT), which may contribute to the effects of oxymetholone. [ 5 ]
The medication will be sold under the brand name Journavx for $15.50 per pill, according to Vertex Pharmaceuticals, the company that developed the new drug. The FDA's sign-off on the medication ...
Designer drugs are structural or functional analogues of controlled substances that are designed to mimic the pharmacological effects of the parent drug while avoiding detection or classification as illegal.