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Most high platelet counts are caused by a reactive process such as infection or inflammation. Once the underlying cause resolves or is managed, platelet counts generally return to normal. However, having a high platelet count can be associated with cancer.
Erythrocytosis, sometimes called polycythaemia, means having a high concentration of red blood cells in your blood. This makes the blood thicker and less able to travel through blood vessels and organs. Many of the symptoms of erythrocytosis are caused by this sluggish flow of blood.
Thrombocytosis (throm-boe-sie-TOE-sis) is a disorder in which your body produces too many platelets. It's called reactive thrombocytosis or secondary thrombocytosis when the cause is an underlying condition, such as an infection.
When high platelets occur as a result of another condition, this is called thrombocytosis. This article explains what high platelet levels mean, symptoms, testing and results, treatment, and more. It also discusses the causes of high platelets, including thrombocytosis and thrombocythemia.
Inflammatory conditions like autoimmune diseases, cancer or trauma, as well as certain infections and iron deficiency, are common causes of a high platelet count. Treatment is directed at the stimulus, and the platelet count returns to normal once resolved.
Thrombocytosis is defined as a high number of circulating platelets in the blood and is usually an incidental finding on a routine FBC. What causes thrombocytosis? This is due to increased production which can be a primary bone marrow problem (rare) or be secondary/reactive (very common) or reduced destruction due to hyposplenism.
The majority of platelet disorders are caused by a genetic fault or mutation. Human beings have about 30,000 to 40,000 different genes, each of which has a function in making an individual person. The genes are arranged in pairs (one of the pair from each parent) on 23 chromosomes – inevitably some of these genes are faulty.