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Cerebral circulation is the movement of blood through a network of cerebral arteries and veins supplying the brain. The rate of cerebral blood flow in an adult human is typically 750 milliliters per minute, or about 15% of cardiac output. Arteries deliver oxygenated blood, glucose and other nutrients to the brain.
The canonical haemodynamic response function (HRF). The spike indicates a brief intense period of neuron stimulation, which requires increased blood and nutrient flow. As the needs of the neuronal activity are met, blood flow returns to homeostatic levels. In haemodynamics, the body must respond to physical activities, external temperature, and ...
Cerebral perfusion pressure. Cerebral perfusion pressure, or CPP, is the net pressure gradient causing cerebral blood flow to the brain (brain perfusion). It must be maintained within narrow limits because too little pressure could cause brain tissue to become ischemic (having inadequate blood flow), and too much could raise intracranial ...
Neuroscience of sleep. The neuroscience of sleep is the study of the neuroscientific and physiological basis of the nature of sleep and its functions. Traditionally, sleep has been studied as part of psychology and medicine. [1] The study of sleep from a neuroscience perspective grew to prominence with advances in technology and the ...
The cerebrospinal fluid circulates in the subarachnoid space around the brain and spinal cord, and in the ventricles of the brain. Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates. CSF is produced by specialised ependymal cells in the choroid plexus of ...
For example, in the understanding the loss of sequential and planning functions due to aging in a study of individuals with Down syndrome, using single positron emission topography, Das [8] found that aging individuals with Down syndrome show a bilateral decreased cerebral blood flow in the temporal-parietal region of the brain. The ...
Cerebral autoregulation. Cerebral autoregulation is a process in mammals that aims to maintain adequate and stable cerebral blood flow. While most systems of the body show some degree of autoregulation, [1] the brain is very sensitive to over- and underperfusion. Cerebral autoregulation plays an important role in maintaining an appropriate ...
Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. [1][2] This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area of the brain is in use, blood flow to that region also increases. [3]