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Denisova 4, a molar. The Denisovans or Denisova hominins (/ d ə ˈ n iː s ə v ə / də-NEE-sə-və) are an extinct species or subspecies of archaic human that ranged across Asia during the Lower and Middle Paleolithic, and lived, based on current evidence, from 285 thousand to 25 thousand years ago. [1]
Denisova 11, genetic tree of ancestors. Denny (Denisova 11) is an ~90,000 year old fossil specimen belonging to a ~13-year-old Neanderthal-Denisovan hybrid girl. [1] [2] To date, she is the only first-generation hybrid hominin ever discovered. [3]
The Denisovan's two HLA-A (A*02 and A*11) and two HLA-C (C*15 and C*12:02) allotypes correspond to common alleles in modern humans, whereas one of the Denisovan's HLA-B allotype corresponds to a rare recombinant allele and the other is absent in modern humans. [48]
Denisovans, Neanderthals and related hybrids may have inhabited the Denisova Cave for extended periods, but perhaps not at the same time. [6] The attribution of the needle and certain other artifacts at the cave, whether to Homo sapiens or to the Denisova hominin (also sometimes known as Homo denisova ), is uncertain.
Neanderthals and Denisovans are more closely related to each other than they are to modern humans, meaning the Neanderthal/Denisovan split occurred after their split with modern humans. [ 14 ] [ 47 ] [ 93 ] [ 113 ] Assuming a mutation rate of 1 × 10 −9 or 0.5 × 10 −9 per base pair (bp) per year, the Neanderthal/Denisovan split occurred ...
By way of protein analysis, researchers concluded that the Xiahe specimen belonged to a population that was closely related to the Denisovan specimens from Denisova Cave. [9] This is the first time that an ancient hominin was successfully identified using only protein analysis. [10] It is the most complete known Denisovan fossil. [10]
Furninha was explored by Nery Delgado at the end of the 19th century. [12] [13] Delgado demonstrated the caves' history of habitation by Neanderthals. [14]Delgado's excavation revealed the existence of animal occupation during the Lower Paleolithic, Neanderthal presence during the Middle Paleolithic, and the presence of Homo sapiens at the end of Chalcolithic.
He has found that people of New Guinea share 4–6% of their genome with the Denisovans, indicating this exchange. [12] The Denisovans are considered cousin to the Neanderthals; both groups are now understood to have migrated out of Africa, with the Neanderthals going into Europe, and the Denisovans heading east about 400,000 years ago.