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  2. What is Angelman syndrome? Colin Farrell opens up about how ...

    www.aol.com/angelman-syndrome-colin-farrell...

    Angelman syndrome is a rare, incurable neurogenetic disorder that can cause intellectual disability, speech and balance problems, developmental delays and possible seizures, according to the Mayo ...

  3. Ultragenyx - Wikipedia

    en.wikipedia.org/wiki/Ultragenyx

    Ultragenyx Pharmaceutical Inc. is an American biopharmaceutical company involved in the research and development of novel products for treatment of rare and ultra-rare genetic diseases for which there are typically no approved treatments and high unmet medical need.

  4. What is Angelman Syndrome, the disease affecting Colin ...

    www.aol.com/angelman-syndrome-disease-affecting...

    "Angelman syndrome shares symptoms and characteristics with other disorders including autism, cerebral palsy and Prader-Willi syndrome," read the Angelman Syndrome Foundation website. "People with ...

  5. Colin Farrell channels son James' Angelman syndrome to launch ...

    www.aol.com/news/colin-farrell-channels-son...

    At the core of Farrell's new organization and its mission: the actor's 20-year-old son James, who lives with Angelman Syndrome. "I want the world to be kind to James," Farrell told People in an ...

  6. John Crowley (businessman) - Wikipedia

    en.wikipedia.org/wiki/John_Crowley_(businessman)

    Crowley left Genzyme to ensure that his children would qualify for a drug developed by the company. He then became founding president and CEO of Orexigen Therapeutics in 2003. In 2004, he became a director at Amicus Therapeutics, based in Cranbury, New Jersey, and in January 2005, he was named the president and CEO of the company. [17]

  7. Angelman syndrome - Wikipedia

    en.wikipedia.org/wiki/Angelman_syndrome

    While Angelman syndrome can be caused by a single mutation in the UBE3A gene, the most common genetic defect leading to Angelman syndrome is a 5- to 7-Mb (megabase) maternal deletion in chromosomal region 15q11.2-q13. [17]

  8. Geron Corporation - Wikipedia

    en.wikipedia.org/wiki/Geron_Corporation

    Geron Corporation has sponsored human clinical trials of several potential anti-cancer products. Imetelstat (GRN163L) is a drug that targets telomerase. [13] In studies conducted at Johns Hopkins University, GRN163L was active against both CD138+ and CD138neg cancer stem cells and eliminated the colony forming potential of both by five weeks. [14]

  9. Colin Farrell launches foundation in honor of son with ...

    www.aol.com/news/colin-farrell-launches...

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