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The human Y chromosome is composed of about 62 million base pairs of DNA, making it similar in size to chromosome 19 and represents almost 2% of the total DNA in a male cell. [54] [55] The human Y chromosome carries 693 genes, 107 of which are protein-coding. [56]
(Gene Gateway) from Human Genome Project (1990-2003) Image Gallery Archive Author Office of Biological and Environmental Research of the U.S. Department of Energy Office of Science, the Biological and Environmental Research Information System, Oak Ridge National Laboratory.
The human Y chromosome showing the SRY gene which codes for a protein regulating sexual differentiation. Sexual differentiation in humans is the process of development of sex differences in humans. It is defined as the development of phenotypic structures consequent to the action of hormones produced following gonadal determination. [1]
At the same time, Jacob & Strong described a case of a patient with Klinefelter syndrome (XXY), [37] which implicated the presence of a Y chromosome in development of maleness. [38] All these observations led to a consensus that a dominant gene that determines testis development must exist on the human Y chromosome. [38]
Pages in category "Genes on human chromosome Y" The following 29 pages are in this category, out of 29 total. This list may not reflect recent changes. ...
In 2021, scientists reported sequencing a complete, female genome (i.e., without the Y chromosome). [4] [3] The human Y chromosome, consisting of 62,460,029 base pairs from a different cell line and found in all males, was sequenced completely in January 2022. [5] The current version of the standard reference genome is called GRCh38.p14 (July ...
•List of human protein-coding genes page 2 covers genes EPHA1–MTMR3 •List of human protein-coding genes page 3 covers genes MTMR4–SLC17A7 •List of human protein-coding genes page 4 covers genes SLC17A8–ZZZ3 NB: Each list page contains 5000 human protein-coding genes, sorted alphanumerically by the HGNC-approved gene symbol.
In humans, the SRY gene is located on short (p) arm of the Y chromosome at position 11.2. Sex-determining region Y protein (SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein/transcription factor) encoded by the SRY gene that is responsible for the initiation of male sex determination in therian mammals (placentals and marsupials). [5]