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Osteons on cross-section of a bone. In osteology, the osteon or haversian system (/ h ə ˈ v ɜːr. ʒ ən /; named for Clopton Havers) is the fundamental functional unit of much compact bone. Osteons are roughly cylindrical structures that are typically between 0.25 mm and 0.35 mm in diameter. [1]
Osteoblasts are cells that group together to form units, called osteons, to produce bone. Runx2 (which may also be known as Cbfa1), and Osx (a zinc finger containing transcription factor) are necessary for osteochondroprogenitor cells to differentiate into the osteoblast cell lineage.
Human bones are densely vascularized as in many other mammals. Even though some authors tried to identify a correlation between endothermy and secondary Haversian reconstruction, this feature is absent in many living mammals (e.g. monotremes, Talpa, flying foxes, Herpestes, Dasypus) and birds (Aratinga, Morococcyx, Nyctidromus, Momotus, Chloroceryle) while others possess only scattered ...
Diameter of canaliculi in human bone is approximately 200 to 900 nm. [1] In bovine tibia diameter of canaliculi was found to vary from 155 to 844 nm (average 426 nm). [ 2 ] In mice humeri it varies from 80 to 710 nm (average 259 nm), while diameter of osteocytic processes varies from 50 to 410 nm (average 104 nm).
A subdiscipline of anatomy, anthropology, and paleontology, osteology is the detailed study of the structure of bones, skeletal elements, teeth, microbone morphology, function, disease, pathology, the process of ossification from cartilaginous molds, and the resistance and hardness of bones . [1]
A bone is a rigid organ [1] that constitutes part of the skeleton in most vertebrate animals. Bones protect the various other organs of the body, produce red and white blood cells, store minerals, provide structure and support for the body, and enable mobility.
As a person ages, some bones fuse, a process which typically lasts until sometime within the third decade of life. Therefore, the number of bones in an individual may be evaluated differently throughout a lifetime. In addition, the bones of the skull and face are counted as separate bones, despite being fused naturally.
It is composed of around 270 bones at birth – this total decreases to around 206 bones by adulthood after some bones get fused together. [1] The bone mass in the skeleton makes up about 14% of the total body weight (ca. 10–11 kg for an average person) and reaches maximum mass between the ages of 25 and 30. [2]