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The opioid epidemic took hold in the U.S. in the 1990s. Percocet, OxyContin and Opana became commonplace wherever chronic pain met a chronic lack of access to quality health care, especially in Appalachia. The Centers for Disease Control and Prevention calls the prescription opioid epidemic the worst of its kind in U.S. history.
In 2022, according to the latest available statistics, almost 80,000 Americans died of opioid overdoses, and another 2.1 million were struggling with opioid addiction. Out of those 80,000, over ...
Letters to the editor on opioid alternatives, Donald Trump’s character, Social Security, Labrador losing, socialism & public school funding. | Opinion Opioids aren’t the only answer for pain.
With opioid use disorder, some people improve with meetings and therapy, others take buprenorphine or methadone for a short time and others need to stay on those drugs.
Long-term opioid use occurs in about 4% of people following their use for trauma or surgery-related pain. [20] In the United States, most heroin users begin by using prescription opioids that may also be bought illegally. [21] [22] People with opioid use disorder are often treated with opioid replacement therapy using methadone or buprenorphine ...
Naltrexone is a long-acting opioid antagonist with few side effects. It is usually prescribed in outpatient medical conditions. Naltrexone blocks the euphoric effects of alcohol and opiates. Naltrexone cuts relapse risk in the first three months by about 36%. [22]
[8] [9] The estimated relative potency of nefopam to morphine indicates that 20 mg of nefopam HCl is the approximate analgesic equal of 12 mg of morphine with comparable analgesic efficacy to morphine, [10] [11] [12] or oxycodone, [13] while nefopam tends to produce fewer side effects, does not produce respiratory depression, [14] and has much ...
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