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  2. Modified-release dosage - Wikipedia

    en.wikipedia.org/wiki/Modified-release_dosage

    Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage). [1] Sustained-release dosage forms are dosage ...

  3. Extended-release morphine - Wikipedia

    en.wikipedia.org/wiki/Extended-release_morphine

    Extended-release (or slow-release) formulations of morphine are those whose effect last substantially longer than bare morphine, availing for, e.g., one administration per day. Conversion between extended-release and immediate-release (or "regular") morphine is easier than conversion to or from an equianalgesic dose of another opioid with ...

  4. Muscle fatigue - Wikipedia

    en.wikipedia.org/wiki/Muscle_fatigue

    Muscle fatigue may be due to precise molecular changes that occur in vivo with sustained exercise. It has been found that the ryanodine receptor present in skeletal muscle undergoes a conformational change during exercise, resulting in "leaky" channels that are deficient in calcium release. These "leaky" channels may be a contributor to muscle ...

  5. Methylphenidate - Wikipedia

    en.wikipedia.org/wiki/Methylphenidate

    Metadate CD capsules contain two types of beads: 30% are immediate-release, and the other 70% are evenly sustained release. [187] Medikinet Retard/CR/Adult/Modified Release tablets are an extended-release oral capsule form of methylphenidate. It delivers 50% of the dosage as IR MPH and the remaining 50% in 3–4 hours. [188] [189]

  6. Anaerobic exercise - Wikipedia

    en.wikipedia.org/wiki/Anaerobic_exercise

    After extended exercise, the release channels can begin to leak and cause muscle fatigue. The anaerobic energy systems are: The alactic anaerobic system, which consists of high energy phosphates , adenosine triphosphate , and creatine phosphate ; and [ 12 ]

  7. 7 blood pressure mistakes that could be throwing off your ...

    www.aol.com/7-blood-pressure-mistakes-could...

    Several key mistakes could throw off the accuracy of blood pressure readings for people who take them at home. The average "normal" blood pressure is 120/80, according to the American Heart ...

  8. Osmotic-controlled release oral delivery system - Wikipedia

    en.wikipedia.org/wiki/Osmotic-controlled_Release...

    Osmotic release systems have a number of major advantages over other controlled-release mechanisms. They are significantly less affected by factors such as pH, food intake, GI motility, and differing intestinal environments. Using an osmotic pump to deliver drugs has additional inherent advantages regarding control over drug delivery rates.

  9. Trump says he'll visit California on Friday to survey ...

    www.aol.com/trump-says-hell-visit-california...

    The remarks come over a week after California Gov. Gavin Newsom invited Trump to visit the state and meet the victims impacted by the wildfires.