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Duloxetine is also used to treat some forms of pain and works by increasing neurotransmitters in the brain. The most common side effects include drowsiness, nausea, constipation, loss of appetite ...
The precise mechanism for its antidepressant and anxiolytic effects is not known. [10] Common side effects include dry mouth, nausea, feeling tired, dizziness, agitation, sexual problems, and increased sweating. [10] Severe side effects include an increased risk of suicide, serotonin syndrome, mania, and liver problems. [10]
Here is a list of Duloxetine side effects that you should report to your physician or care team as soon as possible. They include: Allergic reactions − skin rash, itching, hives, swelling of the ...
Sexual side effects. Some antidepressants, including commonly prescribed ones from the class known as SSRIs (selective serotonin reuptake inhibitors), can cause sexual side effects such as ...
Research on the effectiveness of antidepressants is generally done on people who have severe symptoms, [23] a population that exhibits much weaker placebo responses, [24] meaning that the results may not be extrapolated to the general population that has not (or has not yet) been diagnosed with anxiety or depression. [20]
Selectivity of antidepressant agents are based on the neurotransmitters that are thought to influence symptoms of depression. [27] Drugs that selectively block the reuptake of serotonin and norepinephrine effectively treat depression and are better tolerated than TCAs.
Some people may need antidepressants for a relatively short period (like while grieving the loss of a loved one), or they might need medication long-term, if the depression is chronic.
Approximately 15–50% of people who suddenly stop an antidepressant develop antidepressant discontinuation syndrome. [7] [2] [3] [4] The condition is generally not serious, [2] though about half of people with symptoms describe them as severe. [4] Many restart antidepressants due to the severity of the symptoms. [4]
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