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This requires them to increase their drug dosage to maintain the benefit, and that in turn also increases the unwanted side effects. [78] Long-term opioid use can cause opioid-induced hyperalgesia, which is a condition in which the patient has increased sensitivity to pain. [101] All of the opioids can cause side effects. [70]
Pages in category "Semisynthetic opioids" The following 100 pages are in this category, out of 100 total. This list may not reflect recent changes. 0–9. 7-PET; A.
Oxycodone, a semi-synthetic opioid, is a highly selective full agonist of the μ-opioid receptor (MOR). [ 40 ] [ 41 ] This is the main biological target of the endogenous opioid neuropeptide β-endorphin . [ 18 ]
20 Combination drug formulations containing opioids. 21 See also. 22 References. 23 External links. ... This is a list of opioids, opioid antagonists and inverse ...
Hydromorphone is a semi-synthetic μ-opioid agonist. As a hydrogenated ketone of morphine, it shares the pharmacologic properties typical of opioid analgesics . Hydromorphone and related opioids produce their major effects on the central nervous system and gastrointestinal tract .
As such it is called an opioid as it delivers its effects on pain by interacting with the opioid receptors. It shares many of the side effects of other opioids like constipation, nausea, itching, drowsiness and respiratory depression, but unlike most other opioids it fairly frequently causes hallucinations, nightmares and delusions. It is also ...
Desomorphine [note 1] is a semi-synthetic opioid commercialized by Roche, ... Xylazine, a drug with similar side effects, widespread in the United States; Notes
Like other opioid drugs, pethidine has the potential to cause physical dependence or addiction. The especially severe side effects unique to pethidine among opioids—serotonin syndrome, seizures, delirium, dysphoria, tremor—are primarily or entirely due to the action of its metabolite, norpethidine. [36] [38]