Search results
Results from the WOW.Com Content Network
In the Staedel–Rugheimer pyrazine synthesis (1876), 2-chloroacetophenone is reacted with ammonia to the amino ketone, then condensed and then oxidized to a pyrazine. [5] A variation is the Gutknecht pyrazine synthesis (1879) also based on this selfcondensation , but differing in the way the alpha-ketoamine is synthesised.
Dihydropyrazine and pyrazine synthesis [ edit ] Reaction of the lactam-derived enol phosphates 4 of 2,5-diketopiperazines with palladium catalyzed reactions (reduction, Suzuki and Stille cross-coupling reactions) enables the synthesis of a range of functionalised 1,4-dihydropyrazines 5 which can be aromatized to 1,4- pyrazines 6 in the presence ...
3-Isobutyl-2-methoxypyrazine (2-isobutyl-3-methoxypyrazine [1] also known as Grindstaff pyrazine) is a methoxypyrazine that is very similar to isopropyl methoxy pyrazine except that the alkyl side-group contains an isobutyl group attached to the carbon alpha to the methoxy sidegroup instead of an isopropyl side-group at that same carbon position.
This page was last edited on 14 March 2008, at 19:55 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may ...
The diazinanes have six-membered cyclohexane-like ring but with two carbon atoms replaced by nitrogen atoms.The three isomers of triazinane are distinguished by the positions of their nitrogen atoms, and are referred to as 1,2-diazinane, 1,3-diazinane, and 1,4-diazinane (more commonly called piperazine).
Cascade reactions are often key steps in the efficient total synthesis of complex natural products. The key step in Heathcock's synthesis of dihydroprotodaphniphylline features a highly efficient cascade involving two aldehyde/amine condensations, a Prins-like cyclization, and a 1,5-hydride transfer to afford a pentacyclic structure from an acyclic starting material.
A quinoxaline, also called a benzopyrazine, in organic chemistry, is a heterocyclic compound containing a ring complex made up of a benzene ring and a pyrazine ring. It is isomeric with other naphthyridines including quinazoline, phthalazine and cinnoline. [3] It is a colorless oil that melts just above room temperature.
The phenazine complex [Ru(phen) 2 (dipyrido[3,2-a:2‘,3‘-c]phenazine)] 2+ intercalates into DNA. [3]The more complex phenazines, such as the naphthophenazines, naphthazines, and naphthotolazines, may be prepared by condensing ortho-diamines with ortho-quinones [4] or by the oxidation of an ortho-diamine in the presence of α-naphthol, and by the decomposition of ortho-anilido-(-toluidido ...