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TTF-1 needs to have nuclear staining on immunohistochemistry to count as positive. Cytoplasmic staining is disregarded for diagnostic purposes. [10] Micrograph of a metastatic lung adenocarcinoma (found in the brain) that exhibits nuclear staining (brown) for TTF-1. TTF-1 positive cells are found in the lung as type II pneumocytes and club cells.
22130 Ensembl ENSG00000125482 ENSMUSG00000026803 UniProt Q15361 Q62187 RefSeq (mRNA) NM_001205296 NM_007344 NM_009442 RefSeq (protein) NP_001192225 NP_031370 NP_033468 Location (UCSC) Chr 9: 132.38 – 132.41 Mb Chr 2: 28.95 – 28.98 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Transcription termination factor 1 is a protein that in humans is encoded by the TTF1 gene. References ...
RNA polymerase 1 (also known as Pol I) is, in higher eukaryotes, the polymerase that only transcribes ribosomal RNA (but not 5S rRNA, which is synthesized by RNA polymerase III), a type of RNA that accounts for over 50% of the total RNA synthesized in a cell.
1. Perks/benefits you might receive at a job. 2. Something that signals and/or reveals information. 3. Actions you can take with a particular item. 4. Different meanings of a four-letter word/name.
To actually join the top 1%, a diversified portfolio is essential. Here's how the wealthiest Americans are doing it and what you can learn from their approach as we head into a new year. Invest in ...
Immunohistochemically, prostatic small cell carcinoma are positive for thyroid transcription factor 1 (TTF-1), CD56, chromogranin A, synaptophysin, neuron-specific enolase, calcitonin and bombesin/gastrin-releasing peptide, while lacking, or rarely and weakly expressing, androgen receptor and prostate-specific antigen. [3] [9]
Meanwhile, the S&P 500's current high valuation, which sits at a 21.5 forward 12-month price-to-earnings ratio, per FactSet, is well above the five-year average of 19.7 and the 10-year average of ...
Tumor markers may be used for the following purposes: Monitoring the malignancy; When a malignant tumor is found by the presence of a tumor marker, the level of marker found in the body can be monitored to determine the state of the tumor and how it responds to treatment.
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