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  2. Dabigatran - Wikipedia

    en.wikipedia.org/wiki/Dabigatran

    Dabigatran, sold under the brand name Pradaxa among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. [ 6 ] [ 7 ] Specifically it is used to prevent blood clots following hip or knee replacement and in those with a history of prior clots. [ 6 ]

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood thinners in use. People admitted to hospital requiring blood thinning were started on an infusion of heparin infusion, which thinned blood ...

  4. Discovery and development of direct thrombin inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    In October 2010 the US FDA approved dabigatran etexilate for the prevention of stroke in patients with atrial fibrillation (AF). [ 6 ] [ 10 ] Many pharmaceutical companies have attempted to develop orally bioavailable DTI drugs but dabigatran etexilate is the only one to reach the market.

  5. Vitamin K antagonist - Wikipedia

    en.wikipedia.org/wiki/Vitamin_K_antagonist

    We undertook a post-hoc analysis of data from the ROCKET AF (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation, n = 14,624) for stroke or non-CNS embolism within 30 days after temporary interruptions of 3 days or more, early permanent ...

  6. 5 symptoms men over 40 should never ignore - AOL

    www.aol.com/finance/5-symptoms-men-over-40...

    An online survey conducted by the Cleveland Clinic of 1,174 men 18 years or older, found that 72% of men would rather ... the symptoms can progress over time,” says Fernandez. ... risk of heart ...

  7. More middle-aged adults have been dying from strokes ... - AOL

    www.aol.com/lifestyle/more-middle-aged-adults...

    In recent years, more adults between the ages of 45 and 64 have been dying from strokes, according to a new report from the Centers for Disease Control and Prevention (CDC). Stroke occurs when ...

  8. Vascular dementia - Wikipedia

    en.wikipedia.org/wiki/Vascular_dementia

    It accounts for 50% of all dementias in Japan, 20% to 40% in Europe and 15% in Latin America. 25% of people with stroke develop new-onset dementia within one year of their stroke. One study found that in the United States, the prevalence of vascular dementia in all people over the age of 71 is 2.43%, and another found that the prevalence of the ...

  9. Ozempic: GLP-1 Drugs May Help Prevent 34,000 Heart ... - AOL

    www.aol.com/lifestyle/ozempic-glp-1-drugs-may...

    GLP-1 drugs like Ozempic and Wegovy may help reduce the risk of cardiovascular disease and prevent more than 34,000 heart attacks and strokes a year. Iparraguirre Recio/Getty Images This article ...

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