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The Institute for Clinical and Economic Review (ICER) is a Boston-based independent nonprofit organization that seeks to place a value on medical care by providing comprehensive clinical and cost-effectiveness analyses of treatments, tests, and procedures. [1] ICER was founded in about 2005 by physician-researcher Steven D. Pearson. [1]
As such, the ICER facilitates comparison of interventions across various disease states and treatments. In 2009, NICE set the nominal cost-per-QALY threshold at £50,000 for end-of-life care because dying patients typically benefit from any treatment for a matter of months, making the treatment's QALYs small. [3]
[71] [69] In 2016, real world data evaluating the efficacy of biologics was only publicly available for multiple myeloma through ICER (where biologics were found to be overpriced for their outcomes) [72] and for hepatitis C treatment (which achieved high cure rates—90%—for patients co-infected with HIV and Hep C) through Curant Health. [71 ...
There’s a new one-time treatment for Hemophilia B patients in the market, but it comes with an obscene price tag. A hemophilia drug that just won FDA approval pegs a one-time $3.5 million vial ...
The cost of Factor VIII and similar clotting factors has been described as "highly expensive". [21] The cost of the clotting factors is 80% of all medical costs for people with hemophilia. [23] They are so expensive that gene therapy for haemophilia might be less expensive, especially for people with severe hemophilia. [23]
One of its early initiatives was to secure funding for Comprehensive Hemophilia Diagnostic and Treatment Centers (HTC). [ 2 ] In 1993, the foundation received media coverage of its efforts to hold health care company Baxter International accountable for infecting 10,000 hemophiliac members with AIDS due to HIV contaminated clotting products.
For scale, cutting administrative costs to peer country levels would represent roughly one-third to half the gap. A 2009 study from Price Waterhouse Coopers estimated $210 billion in savings from unnecessary billing and administrative costs, a figure that would be considerably higher in 2015 dollars. [50] Cost variation across hospital regions.
The incremental cost-effectiveness ratio (ICER) is the ratio between the difference in costs and the difference in benefits of two interventions. The ICER may be stated as (C1 – C0)/(E1 – E0) in a simple example where C0 and E0 represent the cost and gain, respectively, from taking no health intervention action.
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