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The most prominent side effects are dizziness and sleepiness. [42] Diphenhydramine is a potent anticholinergic agent and potential deliriant in higher doses. This activity is responsible for the side effects of dry mouth and throat, increased heart rate, pupil dilation, urinary retention, constipation, and, at high doses, hallucinations or ...
Cyproheptadine has been reported to block 85% of 5-HT 2 receptors in the human brain at a dose of 4 mg three times per day (12 mg/day total) and to block 95% of 5-HT 2 receptors in the human brain at a dose of 6 mg three times per day (18 mg/day total) as measured with positron emission tomography (PET). [32]
Weight gain. Some side effects, such as weight gain, occur more frequently with certain types of antidepressant medication. Switching to a new type of antidepressant may help reverse any weight ...
However, another class of antidepressants called MAOIs are considered effective for social anxiety, but they come with many unwanted side effects and are rarely used. Phenelzine was shown to be a good treatment option, but its use is limited by dietary restrictions.
Weight gain. In general, large-scale studies do tend to show that long-term use of antidepressants is associated with weight gain side effects. However, study data on escitalopram and weight ...
Benadryl containing diphenhydramine can interact with alcohol as both are central nervous system (CNS) depressants. Side effects such as drowsiness and dizziness may be enhanced when taking alcohol with diphenhydramine. [16] Mixing diphenhydramine with alcohol can also increase the chances of losing consciousness due to sedation. [17]
At some point before 1986, the Sominex formula had changed to diphenhydramine. [26] On January 17, 1989, the FDA approved the use of diphenhydramine hydrochloride and diphenhydramine citrate; [34] by then, Sominex and Sominex 2 both used at least one of these two chemical compounds. [33]
The most common adverse effect is sedation; this "side-effect" is utilized in many OTC sleeping-aid preparations. Other common adverse effects in first-generation H 1 -antihistamines include dizziness, tinnitus , blurred vision, euphoria , incoordination, anxiety , increased appetite leading to weight gain , insomnia , tremor, nausea and ...