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The heart wall is a three-layered structure with a thick layer of myocardium sandwiched between the inner endocardium and the outer epicardium (also known as the visceral pericardium). The inner endocardium lines the cardiac chambers, covers the cardiac valves , and joins with the endothelium that lines the blood vessels that connect to the heart.
Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; myocardium structure; the electrical conduction system of the heart; the cardiac cycle and cardiac output and how these interact and depend on one another.
The heart is a muscular organ situated in the mediastinum.It consists of four chambers, four valves, two main arteries (the coronary arteries), and the conduction system. The left and right sides of the heart have different functions: the right side receives de-oxygenated blood through the superior and inferior venae cavae and pumps blood to the lungs through the pulmonary artery, and the left ...
The two bundle branches taper out to produce numerous Purkinje fibers, which stimulate individual groups of myocardial cells to contract. [5] The spread of electrical activity through the ventricular myocardium produces the QRS complex on the ECG. Atrial repolarization occurs and is masked during the QRS complex by ventricular depolarization on ...
This function is so significant to normal functioning of the circulatory system that the cardiovascular centre is considered a vital centre of the medulla oblongata. [ 2 ] [ 3 ] Hormones like epinephrine and norepinephrine can affect the cardiovascular centre and cause it to increase the rate of impulses sent to the sinoatrial node , resulting ...
The part of the serous membrane attached to the fibrous membrane is called the parietal pericardium, while the part of the serous membrane attached to the heart is known as the visceral pericardium. The pericardium is present in order to lubricate its movement against other structures within the chest, to keep the heart's position stabilised ...
The moderator band is important because it carries part of the right bundle branch of the atrioventricular bundle of the conduction system of the heart to the anterior papillary muscle. [1] This shortcut across the chamber of the ventricle ensures equal conduction time in the left and right ventricles, allowing for coordinated contraction of ...
cMyBP-C is not essential for sarcomere formation during embryogenesis, but is crucial for sarcomere organization and maintenance of normal cardiac function.Absence of cMyBP-C (Mybpc3-targeted knock-out mice) results in severe cardiac hypertrophy, increased heart-weight-to-body-weight-ratios, enlargement of ventricles, increased myofilament Ca2+ sensitivity and depressed diastolic and systolic ...