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Duloxetine, sold under the brand name Cymbalta among others, [1] is a medication used to treat major depressive disorder, generalized anxiety disorder, obsessive-compulsive disorder, fibromyalgia, neuropathic pain and central sensitization. [10] [11] It is taken by mouth. [10] Duloxetine is a serotonin–norepinephrine reuptake inhibitor (SNRI ...
Some side effects, such as weight gain, occur more frequently with certain types of antidepressant medication. Switching to a new type of antidepressant may help reverse any weight gain you’ve ...
Doctors need to consider potential side effects when prescribing specific antidepressants. ... and duloxetine each had an associated 10-15% higher risk of gaining 5% of baseline weight or more ...
The active metabolite of venlafaxine. It is believed to work in a similar manner, though some evidence suggests lower response rates compared to venlafaxine and duloxetine. It was introduced by Wyeth in May 2008 and was then the third approved SNRI. [8] Duloxetine [9] Cymbalta Irenka Major depressive disorder; Fibromyalgia [10] Generalized ...
The dose should be increased after a minimum of 3 days up to approximately 1.2 mg/kg daily (target dose) as a single or two divided doses (in the morning and late afternoon). For children older than 6 years old, over 70 kg, acute treatment should be started with 40 mg/day orally and increased up to 80 mg/day after a minimum of 3 days.
The saying “knowledge is power” applies well in certain situations — like becoming a leader in your field of expertise or knowing the best places to eat (we all have different skills).
Additionally, some clinically used drugs such as chlorpheniramine, dextromethorphan, and methadone possess SRI properties secondarily to their primary mechanism of action(s) and this contributes to their side effect and drug interaction profiles. A closely related type of drug is a serotonin releasing agent (SRA), an example of which is ...
Such adverse effects are gastrointestinal dysfunction (nausea, diarrhea, epigastric discomfort), effects on the central nervous system (CNS) (anxiety, fatigue, tremor), anticholinergic effects (dry mouth, blurred vision, drowsiness, difficulty in urination) and sexual dysfunction (anorgasmia, low to no libido, erectile dysfunction, numb ...
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related to: duloxetine and ibuprofen interaction anxiety side effects 10 mg reviews