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  2. Candesartan - Wikipedia

    en.wikipedia.org/wiki/Candesartan

    Candesartan is an angiotensin ... metabolite of acetic acid relatively is non-toxic and thus less of a hazard if produced as the drug takes pharmacologic action. ...

  3. Discovery and development of angiotensin receptor blockers

    en.wikipedia.org/wiki/Discovery_and_development...

    Candesartan cilexetil (TCV 116) is a benzimidazole which was developed at Takeda and is an ester carbonate prodrug. In vivo, it is rapidly converted to the much more potent corresponding 7-carboxylic acid, candesartan. In the interaction of candesartan with AT 1 receptor the carboxyl group of the benzimidazole ring plays an important role ...

  4. Angiotensin II receptor blocker - Wikipedia

    en.wikipedia.org/wiki/Angiotensin_II_receptor...

    [8] Candesartan is used experimentally in preventive treatment of migraine. [9] [10] Lisinopril has been found less often effective than candesartan at preventing migraine. [11] The angiotensin II receptor blockers have differing potencies in relation to blood pressure control, with statistically differing effects at the maximal doses. [12]

  5. FDA approves new pain medication as an alternative to opioids ...

    www.aol.com/fda-approves-pain-medication...

    For the first time in two decades, the Food and Drug Administration (FDA) has approved a new class of medication that provides an alternative to addictive opioids for patients looking to manage ...

  6. Frequent Cannabis Use May Damage Working Memory, Decision ...

    www.aol.com/frequent-cannabis-may-damage-working...

    New research shows that heavy lifetime use of cannabis — more than 1,000 times — is associated with reduced activity in areas of the brain involved in working memory. The study adds to ...

  7. Cardiovascular agents - Wikipedia

    en.wikipedia.org/wiki/Cardiovascular_agents

    Although warfarin is commonly prescribed, it exhibits a delayed onset of action, which takes approximately 5 to 7 days to reach its full therapeutic effect. [39] Apart from haemorrhage, jaundice (yellowing of the skin and eyes) is also a common side effect caused by this class of drug. [34]

  8. LeBron James refutes report he was frustrated with Anthony ...

    www.aol.com/sports/lebron-james-refutes-report...

    The NBA world is still reeling from Saturday night's shocking trade between the Dallas Mavericks and Los Angeles Lakers. The trade, which the Mavericks officially announced on Sunday morning, sent ...

  9. Onset of action - Wikipedia

    en.wikipedia.org/wiki/Onset_of_action

    Onset of action is the duration of time it takes for a drug's effects to come to prominence upon administration. With oral administration , it typically ranges anywhere from 20 minutes to over an hour, depending on the drug in question.

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