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  2. PRX-14040 - Wikipedia

    en.wikipedia.org/wiki/PRX-14040

    PRX-14040 is a selective dopamine reuptake inhibitor that was developed by Prexa Pharmaceuticals. [1] [2] [3] It has 28-fold selectivity for the dopamine transporter over the norepinephrine transporter. [2]

  3. L-DOPA - Wikipedia

    en.wikipedia.org/wiki/L-DOPA

    Trade names include Sinemet, Pharmacopa, Atamet, and Stalevo. As a drug, it is used in the clinical treatment of Parkinson's disease and dopamine-responsive dystonia. l-DOPA has a counterpart with opposite chirality, d-DOPA. As is true for many molecules, the human body produces only one of these isomers (the l-DOPA form).

  4. Dopamine reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Dopamine_reuptake_inhibitor

    A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT). Reuptake inhibition is achieved when extracellular dopamine not absorbed by the postsynaptic neuron is blocked from re-entering the presynaptic neuron.

  5. Sympathomimetic drug - Wikipedia

    en.wikipedia.org/wiki/Sympathomimetic_drug

    The mechanisms of sympathomimetic drugs can be direct-acting (direct interaction between drug and receptor), such as α-adrenergic agonists, β-adrenergic agonists, and dopaminergic agonists; or indirect-acting (interaction not between drug and receptor), such as MAOIs, COMT inhibitors, release stimulants, and reuptake inhibitors that increase the levels of endogenous catecholamines.

  6. Over-the-counter drug - Wikipedia

    en.wikipedia.org/wiki/Over-the-counter_drug

    Over-the-counter (OTC) medicines at FamilyDoctor.org, maintained by the American Academy of Family Physicians. Contains extensive information on over-the-counter drugs and their responsible use, including specific guidance on several drug classes in question-and-answer format and information on common drug interactions.

  7. Dopamine antagonist - Wikipedia

    en.wikipedia.org/wiki/Dopamine_antagonist

    Dopamine receptor flow chart. Dopamine receptors are all G protein–coupled receptors, and are divided into two classes based on which G-protein they are coupled to. [1] The D 1-like class of dopamine receptors is coupled to Gα s/olf and stimulates adenylate cyclase production, whereas the D 2-like class is coupled to Gα i/o and thus inhibits adenylate cyclase production.

  8. Vet-Approved Home Treatment for Senior Dogs with Arthritis - AOL

    www.aol.com/vet-approved-home-treatment-senior...

    Related: Dog Arthritis Symptoms and Home Pain Remedies There are several things you can do at home to help an older dog with arthritis, including changing her diet. Photo by manfredxy, Canva

  9. Serotonin–dopamine reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Serotonin–dopamine...

    Medifoxamine (Cledial, Gerdaxyl) is an antidepressant that appears to act as an SDRI as well as a 5-HT 2 receptor antagonist. [3] Sibutramine (Reductil, Meridia, Siredia, Sibutrex) is a withdrawn anorectic that itself as a molecule in vitro is an SNDRI but preferentially an SDRI, with 18.3- and 5.8-fold preference for inhibiting the reuptake of serotonin and dopamine over norepinephrine ...

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