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  2. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [2] Drug interactions can be of three kinds:

  3. Acetaminophen: 4 Things to Know About This Common Over ... - AOL

    www.aol.com/news/2014-01-21-acetaminophen-4...

    For reference, a single tablet of Extra Strength Tylenol contains 500 mg of acetaminophen -- which means just eight tablets would hit the safety threshold. In addition, consuming 1,000 mg (two ...

  4. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban, sold under the brand name Eliquis, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation through directly inhibiting factor Xa.

  5. Paracetamol - Wikipedia

    en.wikipedia.org/wiki/Paracetamol

    Paracetamol, [a] or acetaminophen, [b] is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. [13] [14] [15] It is a widely available over-the-counter drug sold under various brand names, including Tylenol and Panadol. Paracetamol relieves pain in both acute mild migraine and episodic tension headache.

  6. Tylenol (brand) - Wikipedia

    en.wikipedia.org/wiki/Tylenol_(brand)

    The active ingredient of its original flagship product is paracetamol (known in the United States, Canada, and various other countries as acetaminophen), an analgesic and antipyretic. Like the words paracetamol and acetaminophen, the brand name Tylenol is derived from a chemical name for the compound, N-acetyl-para-aminophenol (APAP). [1]

  7. Rumack–Matthew nomogram - Wikipedia

    en.wikipedia.org/wiki/Rumack–Matthew_nomogram

    The original line, sometimes referred to as the Rumack–Matthew line, starts at 200 μg/mL at 4 hours and was published in 1975 by Barry H. Rumack and Henry Matthew. [5] When the NAC study began in 1976, the U.S. Food and Drug Administration (FDA) required a line that was 25% below the original.

  8. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...

  9. When the charge for Tylenol is $4,000, it’s clear the U.S ...

    www.aol.com/charge-tylenol-4-000-clear-224326174...

    The fees included $12,000 for her recovery room, nearly $4,000 for IV Tylenol and a $522 outpatient charge — despite never having been treated as an outpatient at that hospital.

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