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In about one fifth of the dogs with a mastocytoma, feeding instability, vomiting, tarry stools and anemia occur as a result of gastric or duodenal ulcers, [10] in autopsies such ulcers are even detected in more than 80% of patients. [18] About 80% of the dogs with such ulcers are euthanized due to poor general condition. [19]
In severe disease, lesions become persistent and do not respond to immunosuppressive doses of corticosteroids. [1] [2] Cutaneous histiocytosis (CH) is a histiocytic proliferative disorder that primarily involves skin and subcutis and does not extend beyond the local draining lymph nodes. CH occurs in a number of breeds.
Most commonly histiocytomas are found in young dogs and appear as a small, solitary, hairless lump, [6] although Shar Peis may be predisposed to multiple histiocytomas. [7] They are most commonly found on the head, neck, ears, and limbs, and are usually less than 2.5 cm in diameter. [ 8 ]
Two types of mast cell tumors have been identified in cats, a mast cell type similar to dogs and a histiocytic type that appears as subcutaneous nodules and may resolve spontaneously. Young Siamese cats are at an increased risk for the histiocytic type, [ 2 ] although the mast cell type is the most common in all cats and is considered to be ...
In dogs, mammary tumors are the second most common tumor (after skin tumors) over all and the most common tumor in female dogs [2] with a reported incidence of 3.4%. [3] Multiple studies have documented that spaying female dogs when young greatly decreases their risk of developing mammary neoplasia when aged.
The tumor does not often metastasize (occurring in about less than 5 percent of cases), [18] except in puppies and immunocompromised dogs. Metastasis occurs to regional lymph nodes, [citation needed] but can also be seen in the skin, brain, eye, liver, spleen, testicle, rectum and muscle. [19] A biopsy is necessary for diagnosis.
Cancer is the leading cause of death in dogs. [1] It is estimated that 1 in 3 domestic dogs will develop cancer, which is the same incidence of cancer among humans. [2] Dogs can develop a variety of cancers and most are very similar to those found in humans.
Discoid lupus erythematosus is an uncommon autoimmune disease of the skin in dogs. It does not progress to systemic lupus erythematosus in dogs. The most common initial symptom is scaling and loss of pigment on the nose. [34] Juvenile cellulitis, also known as puppy strangles, is a disease that affects puppies. Its cause is unknown, but it is ...