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An artificial lung (AL) is an artificial organ that provides oxygenation of blood and removal of carbon dioxide from the blood. The AL is intended to take over some of the functionality of biological lungs .
Bengt A. Robertson was a Swedish physician and perinatal pathologist. Robertson was primarily known for the development of the synthetic lung surfactant known as Corusurf that brought relief to very small babies suffering from infant respiratory distress syndrome (RDS).
Several potential methods exist for the development of artificial gills. One proposed method is the use of liquid breathing with a membrane oxygenator to solve the problem of carbon dioxide retention, the major limiting factor in liquid breathing.
An artificial organ is a human-made organ device or tissue that is implanted or integrated into a human – interfacing with living tissue – to replace a natural organ, to duplicate or augment a specific function or functions so the patient may return to a normal life as soon as possible. [1]
Pumactant (Artificial Lung Expanding Compound or ALEC) – a mixture of DPPC and PG; Lucinactant (KL4, trade name Surfaxin) – composed of DPPC, palmitoyl-oleoyl phosphatidylglycerol, and palmitic acid, combined with a 21 amino acid synthetic peptide (sinapultide) that mimics the C-terminal helical domain of SP-B. [13] Ventricute - DPPC, rSP-C
Curstedt is primarily known for the development of the synthetic lung surfactant known as Corusurf along with Bengt Robertson. [1] [2] Life
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Although total liquid ventilation (TLV) with completely liquid-filled lungs can be beneficial, [9] the complex liquid-filled tube system required is a disadvantage compared to gas ventilation—the system must incorporate a membrane oxygenator, heater, and pumps to deliver to, and remove from the lungs tidal volume aliquots of conditioned perfluorocarbon (PFC).