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The Prescribing Information follows one of two formats: "physician labeling rule" format or "old" (non-PLR) format. For "old" format labeling a "product title" may be listed first and may include the proprietary name (if any), the nonproprietary name, dosage form(s), and other information about the product.
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Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
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It contains a wide range of information and advice on prescribing for children - from newborn to adolescence. The entries are classified by group of drug, giving cautions for use, side effects , indications and dose for most of the drugs available for children in the UK National Health Service .
This increases the antimicrobial activity by 4- to 32-fold when compared to ampicillin alone. [13] Ampicillin is a time-dependent antibiotic. Its bacterial killing is largely related to the time that drug concentrations in the body remain above the minimum inhibitory concentration (MIC).
Self-prescribing of antibiotics is an example of misuse. [106] Many antibiotics are frequently prescribed to treat symptoms or diseases that do not respond to antibiotics or that are likely to resolve without treatment. Also, incorrect or suboptimal antibiotics are prescribed for certain bacterial infections.
Antibiotics is a peer-reviewed open-access scientific journal covering various aspects of antibiotics research. It is published by MDPI and was established in 2012. The editor-in-chief is Nicholas Dixon ( University of Wollongong ).