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Aging theories based on group selection; Antagonistic pleiotropy hypothesis; C. Cross-linking theory of aging; D. Disposable Soma Theory; ... Immune system theory of ...
Telomere dysfunction during cellular aging (a state in which cells do not divide but are metabolically active) affects the health of the body. [2] Preventing telomere shortening without clearing old cells may lead to the accumulation of these cells in the body and contribute to age-related diseases and tissue dysfunction.
The immunological theory of aging suggests that the immune system weakens as an organism ages. This makes the organism unable to fight infections and less able to destroy old and neoplastic cells. This leads to aging and will eventually lead to death. This theory of aging was developed by Roy Walford in 1969.
Aging theories based on group selection; Antagonistic pleiotropy hypothesis; C. Cross-linking theory of aging; D. Disposable Soma Theory; ... Immune system theory of ...
The two theories; non-adaptive, and adaptive, are used to explain the evolution of senescence, which is the decline in reproduction with age. [8] The non-adaptive theory assumes that the evolutionary deterioration of human age occurs as a result of accumulation of deleterious mutations in the germline. [8]
This is an accepted version of this page This is the latest accepted revision, reviewed on 2 February 2025. Biological process of getting older This article is about ageing specifically in humans. For the ageing of whole organisms including animals, see Senescence. For other uses, see Ageing (disambiguation). Part of a series on Human growth and development Stages Gamete Zygote Embryo Fetus ...
Immunosenescence is the gradual deterioration of the immune system, brought on by natural age advancement. A 2020 review concluded that the adaptive immune system is affected more than the innate immune system. [1] Immunosenescence involves both the host's capacity to respond to infections and the development of long-term immune memory.
Biomedical theories hold that one can age successfully by caring for physical health and minimizing loss in function, whereas psychosocial theories posit that capitalizing upon social and cognitive resources, such as a positive attitude or social support from neighbors, family, and friends, is key to aging successfully. [7]