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2-Fluoronitrobenzene is an organic compound with the formula FC 6 H 4 NO 2. It is one of three isomeric fluoronitrobenzenes. [1] A colorless liquid, it is prepared from 2-nitrochlorobenzene using the Halex process: O 2 NC 6 H 4 Cl + KF → O 2 NC 6 H 4 F + KCl
[2] [3] Common side effects include bone marrow suppression, loss of appetite, diarrhea, vomiting, and psychosis. [2] Anaphylaxis and other allergic reactions occasionally occur. [2] It is unclear if use in pregnancy is safe for the baby. [4] Flucytosine is in the fluorinated pyrimidine analogue family of medications. [2]
4-Fluoronitrobenzene can be hydrogenated to give 4-fluoroaniline, [3] which is a precursor to the fungicide fluoroimide and parafluorofentanyl. Owing to the presence of the electron withdrawing nitro group, the fluoride is a good leaving group in fluoronitrobenzenes. Thus reaction with phenoxide gives the mononitrodiphenylether. [4]
2-Chlorobenzonitrile is an organic compound with the formula ClC 6 H 4 CN. It is a white solid. The compound, one of three isomers of chlorobenzonitrile, is produced industrially by ammoxidation of 2-chlorotoluene. The compound is of commercial interest as a precursor to 2-amino-5-nitrobenzonitrile, a precursor to dyes. [1]
Common side effects include gastrointestinal effects such as nausea, vomiting, and diarrhea, as well as headache and insomnia. Postmarketing surveillance has revealed a variety of relatively rare but serious adverse effects associated with all members of the fluoroquinolone antibacterial class.
Fluorouracil (5-FU, 5-fluorouracil), sold under the brand name Adrucil among others, is a cytotoxic chemotherapy medication used to treat cancer. [3] By intravenous injection it is used for treatment of colorectal cancer , oesophageal cancer , stomach cancer , pancreatic cancer , breast cancer , and cervical cancer . [ 3 ]
4-Nitrobiphenyl is an organic compound with the formula C 6 H 5 −C 6 H 4 NO 2. It is one of three isomers of nitrobiphenyl and probably the most widely used. It is a precursor to the antioxidant 4-aminobiphenyl. 4-Nitrobiphenyl is readily prepared by nitration of biphenyl. [1] It can also be prepared by cross-coupling reactions. [2]
In rare cases, Fluticasone furoate may cause more serious side effects, such as adrenal suppression, glaucoma, cataracts, or growth retardation in children. These side effects are more likely to occur with long-term, high-dose use, although they are still rare. [18] Serious side effects of Fluticasone Furoate include: hives, difficulty breathing,