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  2. ALS - Wikipedia

    en.wikipedia.org/wiki/ALS

    If someone with ALS has signs and symptoms of respiratory failure, they should undergo daytime blood gas analysis [5] to look for hypoxemia (low oxygen in the blood) and hypercapnia (too much carbon dioxide in the blood). [16] If their daytime blood gas analysis is normal, they should then have nocturnal pulse oximetry to look for hypoxemia ...

  3. ALS and MND: Symptoms, causes, treatment - AOL

    www.aol.com/news/what-is-als-symptoms-causes...

    What you need to know about the signs and symptoms, causes, and treatment options for the rare neurological disease. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call

  4. Adrenoleukodystrophy - Wikipedia

    en.wikipedia.org/wiki/Adrenoleukodystrophy

    As an X-linked disorder, ALD presents most commonly in males; however, approximately 50% of heterozygote females show some symptoms later in life. Approximately two-thirds of ALD patients will present with the childhood cerebral form of the disease, which is the most severe form.

  5. Genetics of amyotrophic lateral sclerosis - Wikipedia

    en.wikipedia.org/wiki/Genetics_of_amyotrophic...

    [4] [5] ALS has an oligogenic mode of inheritance, meaning that mutations in two or more genes are required to cause disease. [6] C9orf72 is the most common gene associated with ALS, causing 40% of familial cases of ALS, as well as a small percentage of sporadic cases; [7] it also causes about 25% of familial cases of frontotemporal dementia. [6]

  6. 15 Multiple Sclerosis Symptoms in Females to Have on ... - AOL

    www.aol.com/lifestyle/15-multiple-sclerosis...

    Symptoms of MS can show up differently in men vs. women, says Nicholas Lannen, M.D., a neurologist at Spectrum Health West Michigan. “Women tend to have symptoms more along the lines of pain or ...

  7. Amyotrophic lateral sclerosis research - Wikipedia

    en.wikipedia.org/wiki/Amyotrophic_lateral...

    Using different BAC C9orf72 transgenic mouse model, they were able to study the symptoms of ALS, such as gait abnormalities, anxiety-like behavior, reduced grip strength, and even death rates. [8] Also, the denervation of motor neurons and dysfunction of neurons can be visualized using fluorescent markers to study the neurodegenerative disorder ...

  8. Primary lateral sclerosis - Wikipedia

    en.wikipedia.org/wiki/Primary_lateral_sclerosis

    Symptoms may include difficulty with balance, weakness and stiffness in the legs, and clumsiness. Other common symptoms are spasticity (involuntary muscle contraction due to the stretching of muscle, which depends on the velocity of the stretch) in the hands, feet, or legs, foot dragging , and speech and swallowing problems due to involvement ...

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