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The excessive pressure damages the endothelial layer and the blood–brain barrier, leading to swelling (edema). The predilection toward the posterior brain may be explained by the reduced density of sympathetic innervation in the posterior circulation compared to the anterior circulation (thus a reduced adaptive capacity to fluctuations or ...
Every normal mammalian eye has a scotoma in its field of vision, usually termed its blind spot. This is a location with no photoreceptor cells, where the retinal ganglion cell axons that compose the optic nerve exit the retina. This location is called the optic disc. There is no direct conscious awareness of visual scotomas.
For example, when cytotoxic edema occurs in the endothelial cells of the blood–brain barrier, oncotic cell death contributes to loss of integrity of the blood–brain barrier and promotes the progression to vasogenic edema. [8] When brain edema types are combined, there is typically a primary form and the edema type and context of the cause ...
Thygeson's superficial punctate keratopathy (TSPK) is a disease of the eyes.The causes of TSPK are not currently known, but details of the disease were first published in the Journal of the American Medical Association in 1950 by American ophthalmologist Phillips Thygeson (1903–2002), after whom it is named.
Hypertensive encephalopathy (HE) is general brain dysfunction due to significantly high blood pressure. [3] Symptoms may include headache, vomiting, trouble with balance, and confusion. [1] Onset is generally sudden. [1] Complications can include seizures, posterior reversible encephalopathy syndrome, and bleeding in the back of the eye. [1] [3]
ARIA-E refers to cerebral edema, involving the breakdown of the tight endothelial junctions of the blood-brain barrier and subsequent accumulation of fluid. [3] In a double-blind trial of the humanised monoclonal antibody solanezumab (n = 2042), sixteen patients (11 taking the drug, 5 taking a placebo), or 0.78% developed ARIA-E.
Stye of the upper eyelid 8-year-old boy with an external hordeolum of lower lid. The first sign of a stye is a small, yellowish spot at the center of the bump that develops as pus and expands in the area. [7] Other stye symptoms may include: A lump on the top or bottom eyelid; Localized swelling of the eyelid; Localized pain; Redness; Tenderness
The main symptom is loss of vision, with colors appearing subtly washed out in the affected eye. A pale disc is characteristic of long-standing optic neuropathy. In many cases, only one eye is affected and a person may not be aware of the loss of color vision until the examiner asks them to cover the healthy eye.