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The total oncotic pressure of an average capillary is about 28 mmHg with albumin contributing approximately 22 mmHg of this oncotic pressure, despite only representing 50% of all protein in blood plasma at 35-50 g/L. [6] [7] Because blood proteins cannot escape through capillary endothelium, oncotic pressure of capillary beds tends to draw ...
Typical values for the viscosity of normal human plasma at 37 °C is 1.4 mN·s/m 2. [3] The viscosity of normal plasma varies with temperature in the same way as does that of its solvent water [4];a 3°C change in temperature in the physiological range (36.5°C to 39.5°C)reduces plasma viscosity by about 10%. [5]
The rate at which fluid is filtered across vascular endothelium (transendothelial filtration) is determined by the sum of two outward forces, capillary pressure and colloid osmotic pressure beneath the endothelial glycocalyx (), and two absorptive forces, plasma protein osmotic pressure and interstitial pressure (). The Starling equation is the ...
Capillaroscopy has been used to visualize capillaries in the skin in 2D, and has been reported to observe an average range of capillary pressure of 10.5 to 22.5 mmHg in humans, and an increase in pressure among people with type 1 diabetes and hypertension. Relative to other components of the circulatory system, capillary pressure is low, as to ...
Approximate Normal Value [11] [12] P c: Capillary hydrostatic pressure P c = 0.2 × Arterial Pressure + Venous Pressure 1.2 25mmHg (arteriolar end) 10mmHg (venous end) P i: Tissue interstitial pressure Determined by the compliance of tissue Compliance = volume/Δ pressure Varies by location ≅ −6 mmHg Π c: Capillary oncotic pressure
This may also be called standard range. In contrast, optimal (health) range or therapeutic target is a reference range or limit that is based on concentrations or levels that are associated with optimal health or minimal risk of related complications and diseases. For most substances presented, the optimal levels are the ones normally found in ...
Under normal circumstances the SAAG is < 1.1g/dL (11g/L) because serum oncotic pressure (pulling fluid back into circulation) is exactly counterbalanced by the serum hydrostatic pressure (which pushes fluid out of the circulatory system).
Interstitial oncotic pressure ... Within a wide range of cellular factors ... His 1922 estimate that total length of capillaries in a human body is as long as 100,000 ...