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  2. Dissociative - Wikipedia

    en.wikipedia.org/wiki/Dissociative

    The effects of dissociatives can include sensory dissociation, hallucinations, mania, catalepsy, analgesia and amnesia. [ 4 ] [ 5 ] [ 6 ] According to Pender (1972), "the state has been designated as dissociative anesthesia since the patient truly seems disassociated from his environment."

  3. Post-acute-withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Post-acute-withdrawal_syndrome

    A protracted withdrawal syndrome can occur with symptoms persisting for months to years after cessation of substance use. Benzodiazepines, opioids, alcohol, and any other drug may induce prolonged withdrawal and have similar effects, with symptoms sometimes persisting for years after cessation of use. Psychosis including severe anxiety and ...

  4. Alcohol withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Alcohol_withdrawal_syndrome

    These adverse effects are believed to be due to the neurotoxic effects of repeated withdrawal from alcohol on aberrant neuronal plasticity and cortical damage. Repeated periods of acute intoxication followed by acute detoxification has profound effects on the brain and is associated with an increased risk of seizures as well as cognitive deficits.

  5. Kindling (sedative–hypnotic withdrawal) - Wikipedia

    en.wikipedia.org/wiki/Kindling_(sedative...

    Failure to manage the alcohol withdrawal syndrome appropriately can lead to permanent brain damage or death. [11] Acamprosate, a drug used to promote abstinence from alcohol, an NMDA antagonist drug, reduces excessive glutamate activity in the central nervous system and thereby may reduce excitotoxicity and withdrawal related brain damage. [12 ...

  6. Substance-related disorder - Wikipedia

    en.wikipedia.org/wiki/Substance-related_disorder

    The drugs used are often associated with levels of substance intoxication that alter judgment, perception, attention and physical control, not related with medical effects. It is often thought that the main used substances are illegal drugs and alcohol; however it is becoming more common that prescription drugs and tobacco are a prevalent ...

  7. Physical dependence - Wikipedia

    en.wikipedia.org/wiki/Physical_dependence

    It is debated whether the entire antipsychotic drug class causes true physical dependency, a subset, or if none do. [38] But, if discontinued too rapidly, it could cause an acute withdrawal syndrome. [39] When talking about illicit drugs rebound withdrawal, especially with stimulants, it is sometimes referred to as "coming down" or "crashing".

  8. Drug withdrawal - Wikipedia

    en.wikipedia.org/wiki/Drug_withdrawal

    Drug withdrawal, drug withdrawal syndrome, or substance withdrawal syndrome [1] is the group of symptoms that occur upon the abrupt discontinuation or decrease in the intake of pharmaceutical or recreational drugs. In order for the symptoms of withdrawal to occur, one must have first developed a form of drug dependence.

  9. Substance use disorder - Wikipedia

    en.wikipedia.org/wiki/Substance_use_disorder

    "Substance use pertains to using select substances such as alcohol, tobacco, illicit drugs, etc. that can cause dependence or harmful side effects."On the other hand, substance abuse is the use of drugs such as prescriptions, over-the-counter medications, or alcohol for purposes other than what they are intended for or using them in excessive ...

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