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The deathstalker is one of the most dangerous species of scorpions. [10] [11] Its venom is a powerful mixture of neurotoxins, with a low lethal dose. [12] While a sting from this scorpion is extraordinarily painful, it normally would not kill a healthy adult human.
Parabuthus transvaalicus is a dangerous, medically significant scorpion, which can both sting and spray its kurtoxin venom. [2] The first droplet of venom differs from the rest, and is referred to as "pre-venom". [4] A further potassium channel inhibitor, parabutoxin, has been isolated from the venom of P. transvaalicus. [5]
In another context, the scorpion portrays human sexuality. [10] Scorpions are used in folk medicine in South Asia, especially in antidotes for scorpion stings. [10] One of the earliest occurrences of the scorpion in culture is its inclusion, as Scorpio, in the 12 signs of the Zodiac by Babylonian astronomers during the Chaldean period. [12]
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Charybdotoxin (ChTX) is a 37 amino acid neurotoxin from the venom of the scorpion Leiurus quinquestriatus hebraeus (deathstalker) that blocks calcium-activated potassium channels. [2] This blockade causes hyperexcitability of the nervous system. It is a close homologue of agitoxin and both toxins come from Leiurus quinquestriatus hebraeus.
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Of more than a thousand known species of scorpion, only a few dozen have venom that is dangerous to humans, [6] most notably the bark scorpions, including: Centruroides spp. Deathstalker (Leiurus quinquestriatus) Central and South American Tityus, include the Brazilian yellow scorpion. Androctonus spp. Parabuthus spp. Hottentotta spp.
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