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The next cells passing through Hensen's node become the chordamesoderm. The chordamesoderm has two components: the head process and the notochord. The most anterior part, the head process, is formed by central mesoderm cells migrating anteriorly, behind the prechordal plate mesoderm and toward the rostral tip of the embryo.
The notochord is derived from the embryonic mesoderm and consists of an inner core of vacuolated cells filled with glycoproteins, covered by two helical collagen-elastin sheaths. It lies longitudinally along the rostral-caudal (head to tail) axis of the body, dorsal to the gut tube , and ventral to the dorsal nerve cord .
Axial mesoderm, or chordamesoderm, is the mesoderm in the embryo that lies along the central axis under the neural tube. will give rise to notochord starts as the notochordal process , whose formation finishes at day 20 in humans.
At the onset of gastrulation presumptive mesodermal cells move through the dorsal blastopore lip and form a layer of mesoderm in between the endoderm and the ectoderm. Mesodermal cells migrate along the dorsal midline to give rise to the notochord that develops into the vertebral column. Neuroectoderm overlying the notochord develops into the ...
Ectodermal cells overlying the notochord develop into the neural plate in response to a diffusible signal produced by the notochord. The remainder of the ectoderm gives rise to the epidermis (skin). The ability of the mesoderm to convert the overlying ectoderm into neural tissue is called neural induction.
The segmentation pattern observed in the peripheral nervous system (PNS) derives itself from the paraxial mesoderm. The paraxial mesoderm is arranged along the sides of the notochord and neural tube as repetitive structures called somites. In fact, somites are one of the first embryonic structures to display segmentation.
In each side, the mesoderm remains thin, and is known as the lateral plate. The intermediate mesoderm lies between the paraxial mesoderm and the lateral plate. Between days 13 and 15, the proliferation of extraembryonic mesoderm, primitive streak, and embryonic mesoderm take place. The notochord process occurs between days 15 and 17.
Mesoderm embryonic tissues (paraxial mesoderm, intermediate mesoderm, lateral plate mesoderm and notochord). Also showing the neural tube and the yolk sac.