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Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA). [7] It is used in the treatment of various conditions, most notably obsessive–compulsive disorder but also many other disorders, including hyperacusis, panic disorder, major depressive disorder, trichotillomania, [8] body dysmorphic disorder [9] [10] [11] and chronic pain. [7]
ATC code N06 Psychoanaleptics is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Indeed, seizures are greater risk for concern with maprotiline than with all other tricyclic antidepressants [40] (rising from 75 mg, becoming significant at daily doses ≥ 200 m.g.), including clomipramine. It should thus be prescribed with particular, if not extreme, caution to people with a history of epilepsy/seizures of any other kind. In ...
Status epilepticus is a seizure "lasting longer than 30 minutes or a series of seizures without return to the baseline level of alertness between seizures." [ 12 ] Epilepsia partialis continua is a rare type of focal motor seizure, commonly involving the hands or face , which recurs with intervals of seconds or minutes, lasting for extended ...
Tonic-clonic seizures, also known as Grand Mal seizures, present with continuous stiffening of the body for 10–20 seconds followed by rhythmic jerking. [8] [13] It may be accompanied by an increase in blood pressure, increase in heart rate, urinary incontinence. [8] [5] The person may turn blue if breathing is impaired.
The risk of major congenital malformations for children exposed to these ASMs were within the range for children who were not exposed to any ASMs during pregnancy. [100] People with epilepsy can have healthy pregnancies and healthy babies. However, proper planning and care is essential to minimize the risk of congenital malformations or adverse ...
Dual inhibition of serotonin and noradrenaline reuptake can offer advantages over other antidepressant drugs by treating a wider range of symptoms. [3] They can be especially useful in concomitant chronic or neuropathic pain. [4] SNRIs, along with SSRIs and NRIs, are second-generation antidepressants.
A generalized tonic–clonic seizure, commonly known as a grand mal seizure or GTCS, [1] is a type of generalized seizure that produces bilateral, convulsive tonic and clonic muscle contractions. Tonic–clonic seizures are the seizure type most commonly associated with epilepsy and seizures in general and the most common seizure associated ...
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