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Alcohol education is the planned provision of information and skills relevant to living in a world where alcohol is commonly misused. [3] WHO Global Status Report on Alcohol and Health, highlights the fact that alcohol will be a larger problem in later years, with estimates suggesting it will be the leading cause of disability and death.
Failure to manage the alcohol withdrawal syndrome appropriately can lead to permanent brain damage or death. [48] It has been proposed that brain damage due to alcohol withdrawal may be prevented by the administration of NMDA antagonists, calcium antagonists, and glucocorticoid antagonists. [49]
Discontinuation of alcohol after extended heavy use and associated tolerance development (resulting in dependence) can result in withdrawal. Alcohol withdrawal can cause confusion, paranoia, anxiety, insomnia, agitation, tremors, fever, nausea, vomiting, autonomic dysfunction, seizures, and hallucinations. In severe cases, death can result.
The level of ethanol consumption that minimizes the risk of disease, injury, and death is subject to some controversy. [16] Several studies have found a J-shaped relationship between alcohol consumption and health, [17] [18] [2] [19] meaning that risk is minimized at a certain (non-zero) consumption level, and drinking below or above this level increases risk, with the risk level of drinking a ...
Alcohol detoxification (also known as detox) is the abrupt cessation of alcohol intake in individuals that have alcohol use disorder. This process is often coupled with substitution of drugs that have effects similar to the effects of alcohol in order to lessen the symptoms of alcohol withdrawal. When withdrawal does occur, it results in ...
[2] [3] Globally, excessive alcohol consumption is the seventh leading risk factor for both death and the burden of disease and injury, [4] representing 5.1% of the total global burden of disease and injury, measured in disability-adjusted life years (DALYs). [5] After tobacco, alcohol accounts for a higher burden of disease than any other drug.
Ethanol (alcohol) has a very similar mechanism of tolerance and withdrawal to benzodiazepines, involving the GABA A receptors, NMDA receptors and AMPA receptors, but the majority of research into kindling has primarily focused on alcohol. [6] An intensification of anxiety and other psychological symptoms of alcohol withdrawal also occurs. [10]
Sudden withdrawal from drugs such as alcohol, benzodiazepines, and barbiturates can be extremely dangerous, leading to potentially fatal seizures. For long-term alcoholics, going cold turkey can cause life-threatening delirium tremens. [1] In the case of opioid withdrawal, going "cold turkey" is extremely unpleasant but less dangerous.