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Dengue fever: a Wikipedia clinical review Open Medicine. October 2, 2014. Vol. 8(4), pp.105-115. James M Heilman, Jacob F de Wolff, Graham M Beards, Brian J Basden: Author: James M Heilman, Jacob F de Wolff, Graham M Beards, Brian J Basden, with contributions from multiple Wikipedia contributors
Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]
Dengue fever is a mosquito-borne disease caused by dengue virus, prevalent in tropical and subtropical areas. It is frequently asymptomatic ; if symptoms appear they typically begin 3 to 14 days after infection.
Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
The warning symptoms of severe dengue usually appear between 24 and 48 hours after the fever has disappeared. If a person experiences abdominal pain, vomiting (at least three times in a 24-hour period), bleeding from the nose or gums, and/or feeling fatigued, agitated, or irritable, it is crucial to seek medical attention immediately.
Most dengue fever patients recover in a week, but in severe cases the disease can be life-threatening and require hospitalization since it can result in shock, internal bleeding and even death.
Treatment of acute dengue is supportive, using either oral or intravenous rehydration for mild or moderate disease, and intravenous fluids and blood transfusion for more severe cases. The incidence of dengue fever has increased dramatically since the 1960s, with around 50–100 million people infected yearly. Early descriptions of the condition ...
Dengue fever is caused by infection through viruses of the family Flaviviridae. The illness is most commonly transmitted by Aedes aegypti mosquitoes in tropical and subtropical regions. [54] Dengue virus has four different serotypes, each of which are antigenically related but have limited cross-immunity to reinfection. [55]