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The IOP is higher during sleep. Efficacy of timolol in lowering IOP during the sleep period may be limited. [16] [17] [18] It is a 5–10× more potent beta blocker than propranolol. Timolol is light-sensitive; it is usually preserved with 0.01% benzalkonium chloride (BAC), but also comes BAC-free.
Dorzolamide/timolol, sold under the brand name Cosopt among others, is a medication used to treat high pressure inside the eye including glaucoma. [3] [5] [6] It is a combination of dorzolamide hydrochloride and timolol maleate. [3] It may be used when a beta blocker, like timolol, is not sufficient alone. [7] It is used as an eye drop. [3]
Travoprost/timolol, sold under the brand name Duotrav among others, is a fixed-dose combination medication used for the treatment of glaucoma. [4] [5] ...
Brimonidine/timolol, sold under the brand name Combigan among others, is a fixed-dose combination medication eye drop used for the treatment of glaucoma. [1] It is a combination of brimonidine (an α 2 adrenergic agonist ) and timolol (a β adrenergic blocker ).
Highest concentrations of the acid in the eye are reached one to two hours after application, and its half-life in the aqueous fluid is 1.5 hours. Once it reaches the bloodstream, it is quickly metabolised, so that concentrations in the system do not exceed 25 pg /ml (compared to 20 ng/ml in the eye, which is higher by nearly a factor of 1000).
Brimonidine is indicated for the lowering of intraocular pressure in people with open-angle glaucoma or ocular hypertension. [1] It is also used to reduce redness of the eye. [ 3 ] The gel is indicated for the topical treatment of persistent (nontransient) facial erythema of rosacea in adults 18 years of age or older.
It is an α 2 adrenergic receptor agonist and a weak α 1 adrenergic receptor agonist. [ citation needed ] Topical apraclonidine is administered at a concentration of 1% for the prevention and treatment of post-surgical intraocular pressure (IOP) elevation and 0.5% for short-term adjunctive therapy in patients on maximally tolerated medical ...
Human tears. Tears are a clear liquid secreted by the lacrimal glands (tear gland) found in the eyes of all land mammals. [1] Tears are made up of water, electrolytes, proteins, lipids, and mucins that form layers on the surface of eyes. [2] The different types of tears—basal, reflex, and emotional—vary significantly in composition. [2]
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