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Septic shock refers specifically to distributive shock due to sepsis as a result of infection. [14] Septic shock may be defined as sepsis-induced low blood pressure that persists despite treatment with intravenous fluids. [9] Low blood pressure reduces tissue perfusion pressure, causing the tissue hypoxia that is characteristic of shock.
The SOFA scoring system is useful in predicting the clinical outcomes of critically ill patients. [8] According to an observational study at an Intensive Care Unit (ICU) in Belgium, the mortality rate is at least 50% when the score is increased, regardless of initial score, in the first 96 hours of admission, 27% to 35% if the score remains unchanged, and less than 27% if the score is reduced. [9]
If arterioles dilate, vascular resistance to blood flow goes down and blood pressure goes down, leading to less perfusion and distribution of blood to organs and tissues. Now the most common type of distributive shock is septic shock, from pathogens in the blood, most commonly gram-negative pathogens.
Norepinephrine is often used as a first-line treatment for hypotensive septic shock because evidence shows that there is a relative deficiency of vasopressin when shock continues for 24 to 48 hours. [74] Norepinephrine raises blood pressure through a vasoconstriction effect, with little effect on stroke volume and heart rate. [5]
Distributive shock is a medical condition in which abnormal distribution of blood flow in the smallest blood vessels results in inadequate supply of blood to the body's tissues and organs. [ 1 ] [ 2 ] It is one of four categories of shock , a condition where there is not enough oxygen -carrying blood to meet the metabolic needs of the cells ...
Shock triggered by a serious allergic reaction is known as anaphylactic shock, shock triggered by severe dehydration or blood loss is known as hypovolemic shock, shock caused by sepsis is known as septic shock, etc. Shock itself is a life-threatening condition as a result of compromised body circulation. [22]
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Vasodilatory shock, vasogenic shock, or vasoplegic shock is a medical emergency belonging to shock along with cardiogenic shock, septic shock, allergen-induced shock and hypovolemic shock. When the blood vessels suddenly relax, it results in vasodilation .