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City-building game: Windows, DOS Was released under the GPLv3 for the One Laptop per Child project, and as Micropolis to the general public (the original title of the game). Sinbad and the Throne of the Falcon: 1987 [81] Action Amiga, Apple II, Atari ST, Commodore 64, DOS Cinemaware: SkiFree: 1991 [82] Arcade Windows 3.0 Chris Pirih SkyRoads ...
The long-acting, over-the-counter medication lasts up to 24 hours per dose, according to the Food and Drug Administration (FDA). It reaches peak concentration in your body an hour after you take ...
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives. [5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [5]
The unbound or free fraction of levocetirizine has been reported to be 8%. [1] The true volume of distribution of cetirizine is unknown but is estimated to be 0.3 to 0.45 L/kg. [3] [1] Cetirizine poorly and slowly crosses the blood–brain barrier, which is thought to be due to its chemical properties and its activity as a P-glycoprotein substrate.
Terfenadine acts as a peripherally-selective antihistamine, or antagonist of the histamine H 1 receptor. [3] It is a prodrug, generally completely metabolized to the active form fexofenadine in the liver by the enzyme cytochrome P450 3A4.
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