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Hypothyroidism is common in pregnancy with an estimated prevalence of 2-3% and 0.3-0.5% for subclinical and overt hypothyroidism respectively. [8] Endemic iodine deficiency accounts for most hypothyroidism in pregnant women worldwide while chronic autoimmune thyroiditis is the most common cause of hypothyroidism in iodine sufficient parts of the world.
Postpartum thyroiditis can occur in women with Hashimoto's. [5] In healthy women, Postpartum thyroiditis can occur up to 1 year after delivery and should be differentiated from Hashimoto's thyroiditis as it is treated differently. [136] After giving birth, Tregs rapidly decrease and immune responses are re-established.
Postpartum thyroiditis can recur in subsequent pregnancies. [2] [4] [5] Drug-induced thyroiditis can occur in individuals receiving certain therapies such as amiodarone, interferon-alpha, lithium, tyrosine-kinase inhibitors, and immunotherapies among other drugs. These individuals may develop subacute lymphocytic thyroiditis. [2] [3] [4] [5]
Thyroiditis is generally caused by an immune system attack on the thyroid, resulting in inflammation and damage to the thyroid cells. This disease is often considered a malfunction of the immune system and can be associated with IgG4-related systemic disease, in which symptoms of autoimmune pancreatitis, retroperitoneal fibrosis and noninfectious aortitis also occur.
De Quervain thyroiditis is a self-limiting condition that often goes away without any problems in three to six months. [3] [5] Regardless of the severity of the disease or the type of treatment used, 20–56% of adult patients experienced transient hypothyroidism a few weeks after the hyperthyroid period. [27]
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The accuracy of the diagnosis depends on obtaining tissue from all of the suspicious areas of an abnormal thyroid gland. The reliability of fine needle aspiration is increased when sampling can be guided by ultrasound, and over the last 15 years, this has become the preferred method for thyroid biopsy in North America. [32] [citation needed]
Subacute lymphocytic thyroiditis is a form of thyroiditis. Subacute lymphocytic thyroiditis may occur at any age and is more common in females. A variant of subacute lymphocytic thyroiditis occurs postpartum: postpartum thyroiditis. Both of these entities can be considered subtypes of Hashimoto's thyroiditis and have an autoimmune basis. Anti ...